TY - JOUR
T1 - Eyelid Merkel cell carcinoma in a patient treated with golimumab
AU - Hanafi, H
AU - Verdijk, R M
AU - Paridaens, D
PY - 2018/2
Y1 - 2018/2
N2 - PURPOSE: To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA).METHODS: Interventional case report.RESULTS: A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid.CONCLUSIONS: Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.
AB - PURPOSE: To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA).METHODS: Interventional case report.RESULTS: A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid.CONCLUSIONS: Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.
KW - Aged
KW - Antibodies, Monoclonal/adverse effects
KW - Arthritis, Rheumatoid/drug therapy
KW - Carcinoma, Merkel Cell/chemically induced
KW - Chronic Disease
KW - Combined Modality Therapy
KW - Dose Fractionation, Radiation
KW - Eyelid Neoplasms/chemically induced
KW - Female
KW - Humans
KW - Immunosuppressive Agents/adverse effects
KW - Ophthalmologic Surgical Procedures
KW - Radiotherapy Dosage
KW - Reconstructive Surgical Procedures
KW - Tumor Necrosis Factor-alpha/antagonists & inhibitors
U2 - 10.1080/01676830.2017.1353118
DO - 10.1080/01676830.2017.1353118
M3 - Letter
C2 - 28841334
VL - 37
SP - 21
EP - 25
IS - 1
ER -