TY - JOUR
T1 - Axonal loss in a patient with anterior ischemic optic neuropathy as measured with scanning laser polarimetry
AU - Colen, T P
AU - van Everdingen, J A
AU - Lemij, H G
PY - 2000/12
Y1 - 2000/12
N2 - PURPOSE: To report Nerve Fiber Analyzer (NFA/GDx; Laser Diagnostic Technologies, San Diego, California) measurements in a patient during the early phase of an anterior ischemic optic neuropathy.METHODS: Case report. A 58-year old man with acute anterior ischemic optic neuropathy had repeated NFA/GDx scans of the nerve fiber layer adjacent to the optic nerve head of the involved eye, as well as repeated HFA 30.2 (Humphrey Field Analyzer; Humphrey Systems, San Leandro, California) visual field examinations.RESULTS: At presentation (day 0), he had a normal superior nerve fiber bundle on the NFA/GDx, with a deep inferior hemifield scotoma. By day 21 and day 36, the superior nerve fiber bundle thinned on the NFA/GDx, whereas the scotoma remained practically unchanged.CONCLUSION: These findings suggest that after the onset of an anterior ischemic optic neuropathy, acute loss of axonal function results in scotoma, presumably from ischemia. This is followed by a gradual disappearance of nerve fiber tissue, as measured with the NFA/GDx, within several weeks.
AB - PURPOSE: To report Nerve Fiber Analyzer (NFA/GDx; Laser Diagnostic Technologies, San Diego, California) measurements in a patient during the early phase of an anterior ischemic optic neuropathy.METHODS: Case report. A 58-year old man with acute anterior ischemic optic neuropathy had repeated NFA/GDx scans of the nerve fiber layer adjacent to the optic nerve head of the involved eye, as well as repeated HFA 30.2 (Humphrey Field Analyzer; Humphrey Systems, San Leandro, California) visual field examinations.RESULTS: At presentation (day 0), he had a normal superior nerve fiber bundle on the NFA/GDx, with a deep inferior hemifield scotoma. By day 21 and day 36, the superior nerve fiber bundle thinned on the NFA/GDx, whereas the scotoma remained practically unchanged.CONCLUSION: These findings suggest that after the onset of an anterior ischemic optic neuropathy, acute loss of axonal function results in scotoma, presumably from ischemia. This is followed by a gradual disappearance of nerve fiber tissue, as measured with the NFA/GDx, within several weeks.
KW - Axons/pathology
KW - Diagnostic Techniques, Ophthalmological
KW - Humans
KW - Male
KW - Middle Aged
KW - Nerve Fibers/pathology
KW - Ophthalmoscopes
KW - Optic Nerve/pathology
KW - Optic Neuropathy, Ischemic/complications
KW - Scotoma/diagnosis
KW - Visual Field Tests
U2 - 10.1016/s0002-9394(00)00627-9
DO - 10.1016/s0002-9394(00)00627-9
M3 - Letter
C2 - 11124316
SN - 0002-9394
VL - 130
SP - 847
EP - 850
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 6
ER -