Autologous Translocation of the Retinal Pigment Epithelium and Choroid in the Treatment of Exudative Age-related Macular Degeneration

Kristel Maaijwee

    Onderzoeksoutput: Typen scriptie/masterproefDoctoraatthesis

    Samenvatting

    Age-related macular degeneration (AMD) is the most important cause of irreversible legal blindness in elderly persons in industrialized countries. AMD has two forms: atrophic (dry) and exudative (wet). In the wet form, abnormal blood vessels, arising from the choriocapillaris (choroidal neovascularization, CNV) underneath the macula, grow through ruptures in the Bruch’s membrane, into the sub-retinal pigment epithelium (RPE) space or into the subretinal space, or a combination of both. Blood and serum leakage from the CNV below the RPE and/or below and within the retina are harmful and fi nally causes irreversible damage to the photoreceptors of the overlying macula which results in a central scotoma.
    Originele taal-2Engels
    KwalificatieDoctor in de Filosofie
    Toekennende instantie
    Begeleider(s)/adviseur
    • van Meurs, Jan, Begeleider
    Plaats van publicatieRotterdam
    StatusGepubliceerd - 2008

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