Trypan blue capsular staining to "find" the leading edge of a "lost" capsulorhexis

Peter W T de Waard, Camille J Budo, Gerrit R J Melles

    Research output: Contribution to journalArticleResearchpeer-review


    PURPOSE: To describe an effective surgical technique to visualize an obscured leading edge of a capsulorhexis.

    DESIGN: Prospective, interventional case series.

    METHODS: In six eyes of six patients in which the capsulorhexis was started but could no longer be seen during surgery, the anterior chamber was irrigated to remove all viscoelastic, and 0.3-ml trypan blue 0.06% was applied onto the anterior lens capsule to stain and visualize the leading edge of the capsulorhexis.

    RESULTS: In all patients, the leading edge of the capsulorhexis was quickly visualized by using the dye. No adverse reactions were observed up to 1 year after surgery.

    CONCLUSION: Trypan blue staining of the anterior lens capsule is an effective and apparently safe technique to "find" a "lost" capsulorhexis during surgery.

    Original languageEnglish
    Pages (from-to)271-2
    Number of pages2
    JournalAmerican Journal of Ophthalmology
    Issue number2
    Publication statusPublished - Aug 2002


    • Capsulorhexis/methods
    • Coloring Agents
    • Humans
    • Lens Capsule, Crystalline/surgery
    • Phacoemulsification
    • Prospective Studies
    • Staining and Labeling/methods
    • Trypan Blue


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