Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study

Kristel Maaijwee; Twan Koolen; Dagmar Rosenbrand; Elmer Jacobs; Sander Kleinheerenbrink; Arjan Knulst; Joop Bos; Wim P Holland; Alex Brouwer; Jan C van Meurs; Sander Schutte

doi:10.1167/iovs.07-1220

Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study

Kristel Maaijwee, Twan Koolen, Dagmar Rosenbrand, Elmer Jacobs, Sander Kleinheerenbrink, Arjan Knulst, Joop Bos, Wim P Holland, Alex Brouwer, Jan C van Meurs, Sander Schutte

Vitreoretinal surgery

Research output: Contribution to journal › Article › Research › peer-review

Abstract

PURPOSE: During retinal pigment epithelium (RPE) and choroid graft translocation in the treatment of patients with exudative age-related macular degeneration, the adhesion of the graft to the translocation instrument complicated its submacular release. Vibration of the instrument improved the release of the graft. This study was conducted to validate the effectiveness of the principle of vibration and to determine the threshold amplitude and frequency required for development of an optimized instrument.

METHODS: An experimental in vitro model with fresh porcine RPE-choroid grafts was used. Release of the graft was studied by a masked observer for amplitudes in the range of 0.05 to 1.2 mm and frequencies in the range of 25 to 200 Hz in the horizontal plane.

RESULTS: The minimum threshold amplitude required to release the graft was approximately 0.15 mm from a frequency of 100 Hz and higher.

CONCLUSIONS: This study confirmed the clinical experience that vibration of an instrument induces the release of the RPE-choroid graft. The minimum threshold amplitude and frequency needed for optimum tissue release were estimated.

Original language	English
Pages (from-to)	1629-32
Number of pages	4
Journal	Investigative ophthalmology & visual science
Volume	49
Issue number	4
DOIs	https://doi.org/10.1167/iovs.07-1220
Publication status	Published - Apr 2008

Keywords

Animals
Choroid/transplantation
Models, Theoretical
Ophthalmologic Surgical Procedures/instrumentation
Pigment Epithelium of Eye/transplantation
Sensory Thresholds
Swine
Vibration

Access to Document

10.1167/iovs.07-1220

Cite this

Maaijwee, K., Koolen, T., Rosenbrand, D., Jacobs, E., Kleinheerenbrink, S., Knulst, A., Bos, J., Holland, W. P., Brouwer, A., van Meurs, J. C., & Schutte, S. (2008). Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study. Investigative ophthalmology & visual science, 49(4), 1629-32. https://doi.org/10.1167/iovs.07-1220

@article{3ca1bc1f1a8944698c3b0ff041996178,

title = "Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study",

abstract = "PURPOSE: During retinal pigment epithelium (RPE) and choroid graft translocation in the treatment of patients with exudative age-related macular degeneration, the adhesion of the graft to the translocation instrument complicated its submacular release. Vibration of the instrument improved the release of the graft. This study was conducted to validate the effectiveness of the principle of vibration and to determine the threshold amplitude and frequency required for development of an optimized instrument.METHODS: An experimental in vitro model with fresh porcine RPE-choroid grafts was used. Release of the graft was studied by a masked observer for amplitudes in the range of 0.05 to 1.2 mm and frequencies in the range of 25 to 200 Hz in the horizontal plane.RESULTS: The minimum threshold amplitude required to release the graft was approximately 0.15 mm from a frequency of 100 Hz and higher.CONCLUSIONS: This study confirmed the clinical experience that vibration of an instrument induces the release of the RPE-choroid graft. The minimum threshold amplitude and frequency needed for optimum tissue release were estimated.",

keywords = "Animals, Choroid/transplantation, Models, Theoretical, Ophthalmologic Surgical Procedures/instrumentation, Pigment Epithelium of Eye/transplantation, Sensory Thresholds, Swine, Vibration",

author = "Kristel Maaijwee and Twan Koolen and Dagmar Rosenbrand and Elmer Jacobs and Sander Kleinheerenbrink and Arjan Knulst and Joop Bos and Holland, {Wim P} and Alex Brouwer and {van Meurs}, {Jan C} and Sander Schutte",

year = "2008",

month = apr,

doi = "10.1167/iovs.07-1220",

language = "English",

volume = "49",

pages = "1629--32",

number = "4",

}

Maaijwee, K, Koolen, T, Rosenbrand, D, Jacobs, E, Kleinheerenbrink, S, Knulst, A, Bos, J, Holland, WP, Brouwer, A, van Meurs, JC & Schutte, S 2008, 'Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study', Investigative ophthalmology & visual science, vol. 49, no. 4, pp. 1629-32. https://doi.org/10.1167/iovs.07-1220

TY - JOUR

T1 - Threshold amplitude and frequency for ocular tissue release from a vibrating instrument

T2 - an experimental study

AU - Maaijwee, Kristel

AU - Koolen, Twan

AU - Rosenbrand, Dagmar

AU - Jacobs, Elmer

AU - Kleinheerenbrink, Sander

AU - Knulst, Arjan

AU - Bos, Joop

AU - Holland, Wim P

AU - Brouwer, Alex

AU - van Meurs, Jan C

AU - Schutte, Sander

PY - 2008/4

Y1 - 2008/4

N2 - PURPOSE: During retinal pigment epithelium (RPE) and choroid graft translocation in the treatment of patients with exudative age-related macular degeneration, the adhesion of the graft to the translocation instrument complicated its submacular release. Vibration of the instrument improved the release of the graft. This study was conducted to validate the effectiveness of the principle of vibration and to determine the threshold amplitude and frequency required for development of an optimized instrument.METHODS: An experimental in vitro model with fresh porcine RPE-choroid grafts was used. Release of the graft was studied by a masked observer for amplitudes in the range of 0.05 to 1.2 mm and frequencies in the range of 25 to 200 Hz in the horizontal plane.RESULTS: The minimum threshold amplitude required to release the graft was approximately 0.15 mm from a frequency of 100 Hz and higher.CONCLUSIONS: This study confirmed the clinical experience that vibration of an instrument induces the release of the RPE-choroid graft. The minimum threshold amplitude and frequency needed for optimum tissue release were estimated.

AB - PURPOSE: During retinal pigment epithelium (RPE) and choroid graft translocation in the treatment of patients with exudative age-related macular degeneration, the adhesion of the graft to the translocation instrument complicated its submacular release. Vibration of the instrument improved the release of the graft. This study was conducted to validate the effectiveness of the principle of vibration and to determine the threshold amplitude and frequency required for development of an optimized instrument.METHODS: An experimental in vitro model with fresh porcine RPE-choroid grafts was used. Release of the graft was studied by a masked observer for amplitudes in the range of 0.05 to 1.2 mm and frequencies in the range of 25 to 200 Hz in the horizontal plane.RESULTS: The minimum threshold amplitude required to release the graft was approximately 0.15 mm from a frequency of 100 Hz and higher.CONCLUSIONS: This study confirmed the clinical experience that vibration of an instrument induces the release of the RPE-choroid graft. The minimum threshold amplitude and frequency needed for optimum tissue release were estimated.

KW - Animals

KW - Choroid/transplantation

KW - Models, Theoretical

KW - Ophthalmologic Surgical Procedures/instrumentation

KW - Pigment Epithelium of Eye/transplantation

KW - Sensory Thresholds

KW - Swine

KW - Vibration

U2 - 10.1167/iovs.07-1220

DO - 10.1167/iovs.07-1220

M3 - Article

C2 - 18385084

SN - 0146-0404

VL - 49

SP - 1629

EP - 1632

JO - Investigative ophthalmology & visual science

JF - Investigative ophthalmology & visual science

IS - 4

ER -

Threshold amplitude and frequency for ocular tissue release from a vibrating instrument: an experimental study

Abstract

Keywords

Access to Document

Fingerprint

Cite this