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The role of thrombin in proliferative vitreoretinopathy
Jeroen Bastiaans
, Jan C van Meurs
, Verena C Mulder
, Nicole M A Nagtzaam
, Marja Smits-te Nijenhuis
, Diana C M Dufour-van den Goorbergh
, P Martin van Hagen
, Herbert Hooijkaas
, Willem A Dik
Vitreoretinal surgery
Rotterdam Ophthalmic Institute
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Keyphrases
Proliferative Vitreoretinopathy
100%
Thrombin
100%
Antithrombin Activity
36%
Vitrectomy
27%
Retinal Detachment
18%
Platelet-derived Growth factor-BB (PDGF-BB)
18%
ARPE-19 Cells
18%
Granulocyte Colony-stimulating Factor (G-CSF)
18%
Chemokine (C-C motif) Ligand 2 (CCL2)
18%
Hirudin
18%
Treatment Options
9%
Chemokines
9%
Interleukin-6
9%
Growth Factors
9%
Macular Hole
9%
Macular Pucker
9%
ARPE-19
9%
MRNA Level
9%
CXCL8
9%
Profibrotic
9%
Multiplex
9%
Quantitative PCR
9%
RPE Cells
9%
Potential Treatments
9%
Vitreous Samples
9%
Chromogenic Substrate
9%
Chemokine (C-X-C motif) Ligand 8
9%
Medicine and Dentistry
Proliferative Vitreoretinopathy
100%
Thrombin
100%
Vitreous
72%
Vitrectomy
27%
Retinal Detachment
18%
Gamma Chemokine
18%
Granulocyte Macrophage Colony Stimulating Factor
18%
Hirudin
18%
Chemokine
9%
Epileptic Absence
9%
Epiretinal Membrane
9%
Macular Hole
9%
Growth Factor
9%
Platelet Derived Growth Factor B
9%
Cytokine
9%
Platelet Derived Growth Factor BB
9%
Chromogenic Substrate
9%
Real-Time Polymerase Chain Reaction
9%
Interleukin-6
9%
Nursing and Health Professions
Vitreoretinopathy
100%
Thrombin
100%
Vitrectomy
27%
Retina Detachment
18%
Hirudin
18%
Gamma Chemokine
18%
Platelet Derived Growth Factor BB
9%
Chromogenic Substrate
9%
Epiretinal Membrane
9%
mRNA Expression Level
9%
Granulocyte Macrophage Colony Stimulating Factor
9%
Platelet Derived Growth Factor B
9%
Chemokine
9%
Epileptic Absence
9%
Growth Factor
9%
Retina Macula Hole
9%
Immunology and Microbiology
Thrombin
100%
Granulocyte Macrophage Colony-Stimulating Factor
28%
Gamma Chemokine
28%
Cytokine
14%
Platelet Derived Growth Factor BB
14%
Growth Factor
14%
Interleukin-6
14%
mRNA Expression Level
14%
Chemokine
14%
CCL2
14%
Platelet Derived Growth Factor B
14%
Real-Time Polymerase Chain Reaction
14%
Veterinary Science and Veterinary Medicine
Granulocyte Macrophage Colony-Stimulating Factor
100%
Platelet-Derived Growth Factor
50%
Growth Factor
50%
PDGFB
50%