The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis

G S Baarsma; E La Hey; E Glasius; J de Vries; A Kijlstra

doi:10.1016/0002-9394(87)90406-5

The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis

G S Baarsma, E La Hey, E Glasius, J de Vries, A Kijlstra

Medical retina and Uveitis

Research output: Contribution to journal › Article › Research › peer-review

Abstract

We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme level above 50 units/l (mean + 2 S.D.), the sensitivity of the test was 84%, the specificity was 95%, and the predictive value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 mg/l (mean + 2 S.D.), the specificity was 76%, and the predictive value was 12%.

Original language	English
Pages (from-to)	211-7
Number of pages	7
Journal	American Journal of Ophthalmology
Volume	104
Issue number	3
DOIs	https://doi.org/10.1016/0002-9394(87)90406-5
Publication status	Published - 15 Sept 1987

Keywords

Adult
Aging/blood
Eye Diseases/complications
Female
Forecasting
Humans
Longitudinal Studies
Male
Middle Aged
Muramidase/blood
Peptidyl-Dipeptidase A/blood
Sarcoidosis/complications
Uveitis/classification

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title = "The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis",

abstract = "We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme level above 50 units/l (mean + 2 S.D.), the sensitivity of the test was 84%, the specificity was 95%, and the predictive value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 mg/l (mean + 2 S.D.), the specificity was 76%, and the predictive value was 12%.",

keywords = "Adult, Aging/blood, Eye Diseases/complications, Female, Forecasting, Humans, Longitudinal Studies, Male, Middle Aged, Muramidase/blood, Peptidyl-Dipeptidase A/blood, Sarcoidosis/complications, Uveitis/classification",

author = "Baarsma, {G S} and {La Hey}, E and E Glasius and {de Vries}, J and A Kijlstra",

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doi = "10.1016/0002-9394(87)90406-5",

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T1 - The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis

AU - Baarsma, G S

AU - La Hey, E

AU - Glasius, E

AU - de Vries, J

AU - Kijlstra, A

PY - 1987/9/15

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N2 - We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme level above 50 units/l (mean + 2 S.D.), the sensitivity of the test was 84%, the specificity was 95%, and the predictive value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 mg/l (mean + 2 S.D.), the specificity was 76%, and the predictive value was 12%.

AB - We determined the serum angiotensin converting enzyme and lysozyme levels in 221 patients with uveitis and in 67 control subjects. Angiotensin converting enzyme and lysozyme levels were found to be age dependent. Of the 221 patients, 12 had sarcoidosis. In patients with uveitis who had an angiotensin converting enzyme level above 50 units/l (mean + 2 S.D.), the sensitivity of the test was 84%, the specificity was 95%, and the predictive value was 47%. In these same patients the sensitivity was 60% for a lysozyme level above 8 mg/l (mean + 2 S.D.), the specificity was 76%, and the predictive value was 12%.

KW - Adult

KW - Aging/blood

KW - Eye Diseases/complications

KW - Female

KW - Forecasting

KW - Humans

KW - Longitudinal Studies

KW - Male

KW - Middle Aged

KW - Muramidase/blood

KW - Peptidyl-Dipeptidase A/blood

KW - Sarcoidosis/complications

KW - Uveitis/classification

U2 - 10.1016/0002-9394(87)90406-5

DO - 10.1016/0002-9394(87)90406-5

M3 - Article

C2 - 2820230

SN - 0002-9394

VL - 104

SP - 211

EP - 217

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 3

ER -

The predictive value of serum angiotensin converting enzyme and lysozyme levels in the diagnosis of ocular sarcoidosis

Abstract

Keywords

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