Retinal pigment epithelium (RPE)-choroid graft translocation in the treatment of an RPE tear: preliminary results

K Maaijwee, A M Joussen, B Kirchhof, J C van Meurs

Research output: Contribution to journalArticleResearchpeer-review


AIM: To investigate whether retinal pigment epithelium (RPE)-choroid translocation would be a suitable treatment for RPE tears, which have a poor prognosis and are encountered more often since the introduction of anti-(vascular endothelial growth factor (VEGF)) therapy for exudative age-related macular degeneration (AMD).

METHODS: Prospective interventional case series of six eyes of six patients with AMD with an RPE tear treated with an RPE-choroid translocation. The RPE tear occurred in a vascularised pigment epithelium detachment in four patients and after treatment in the other two. Preoperative and postoperative evaluation included ETDRS visual acuity (VA) and fixation testing. The follow-up period ranged from 6 months to 2 years.

RESULTS: The mean preoperative VA was 20/160 (range 20/400-20/80). The mean VA at the last examination after surgery was 20/80 (range 1/60-20/50). One of the six patients had a preoperative VA of >/=20/80, and four had a VA of 20/80 or better at their last examination. Foveal fixation on the graft was present in five of the six eyes up to the last examination.

CONCLUSION: These preliminary data show that an RPE-choroid translocation may be a treatment option for patients with an RPE tear.

Original languageEnglish
Pages (from-to)526-9
Number of pages4
JournalBritish Journal of Ophthalmology
Issue number4
Publication statusPublished - Apr 2008


  • Aged
  • Aged, 80 and over
  • Choroid/transplantation
  • Choroidal Neovascularization/complications
  • Female
  • Humans
  • Macular Degeneration/complications
  • Male
  • Pigment Epithelium of Eye/injuries
  • Postoperative Complications
  • Prospective Studies
  • Treatment Outcome
  • Visual Acuity
  • Vitrectomy


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