PURPOSE: To describe the radiologic, histopathologic, and cytogenetic features of an orbital chondrosarcoma developing in a patient with Paget disease.
METHODS: A 64-year-old woman presented with rapidly progressive proptosis of her right eye. Computed tomographic scans, histopathologic examination, and cytogenetic analysis were performed.
RESULTS: Computed tomographic scans disclosed osseous changes of the temporal and frontal bones, with areas of high density consistent with Paget disease. A soft-tissue tumor in the right lateral orbital wall was consistent with Paget sarcoma. On histology, a chondrosarcoma was diagnosed, which was confirmed by fluorescent in situ hybridization.
CONCLUSION: This is a unique case of orbital chondrosarcoma developing in a patient with Paget disease.
|Number of pages||3|
|Journal||American Journal of Ophthalmology|
|Publication status||Published - May 1999|
- Chondrosarcoma/diagnostic imaging
- DNA, Neoplasm/analysis
- Frontal Bone/pathology
- In Situ Hybridization, Fluorescence
- Middle Aged
- Orbital Neoplasms/diagnostic imaging
- Osteitis Deformans/complications
- Temporal Bone/pathology
- Tomography, X-Ray Computed