TY - JOUR
T1 - Ocular infections in sub-Saharan Africa in the context of high HIV prevalence
AU - Schaftenaar, Erik
AU - van Gorp, Eric C M
AU - Meenken, Christina
AU - Osterhaus, Albert D M E
AU - Remeijer, Lies
AU - Struthers, Helen E
AU - McIntyre, James A
AU - Baarsma, G Seerp
AU - Verjans, Georges M G M
AU - Peters, Remco P H
N1 - © 2014 John Wiley & Sons Ltd.
PY - 2014/9
Y1 - 2014/9
N2 - Healthy eyes and good vision are important determinants of populations' health across the globe. Sub-Saharan Africa is affected by simultaneous epidemics of ocular infections and human immunodeficiency virus (HIV). Ocular infection and its complications, along with cataract and ocular trauma, are common conditions in this region with great impact on daily life. In this review, we discuss the epidemiology, clinical manifestations and microbial aetiology of the most important infectious ocular conditions in sub-Saharan Africa: conjunctivitis, keratitis and uveitis. We focus specifically on the potential association of these infections with HIV infection, including immune recovery uveitis. Finally, challenges and opportunities for clinical management are discussed, and recommendations made to improve care in this neglected but very important clinical field.
AB - Healthy eyes and good vision are important determinants of populations' health across the globe. Sub-Saharan Africa is affected by simultaneous epidemics of ocular infections and human immunodeficiency virus (HIV). Ocular infection and its complications, along with cataract and ocular trauma, are common conditions in this region with great impact on daily life. In this review, we discuss the epidemiology, clinical manifestations and microbial aetiology of the most important infectious ocular conditions in sub-Saharan Africa: conjunctivitis, keratitis and uveitis. We focus specifically on the potential association of these infections with HIV infection, including immune recovery uveitis. Finally, challenges and opportunities for clinical management are discussed, and recommendations made to improve care in this neglected but very important clinical field.
KW - Africa South of the Sahara/epidemiology
KW - Conjunctivitis/complications
KW - Epidemics
KW - Eye Infections/complications
KW - HIV Infections/complications
KW - Humans
KW - Keratitis/complications
KW - Uveitis/complications
U2 - 10.1111/tmi.12350
DO - 10.1111/tmi.12350
M3 - Review article
C2 - 25039335
SN - 1360-2276
VL - 19
SP - 1003
EP - 1014
JO - Tropical medicine & international health : TM & IH
JF - Tropical medicine & international health : TM & IH
IS - 9
ER -