TY - JOUR
T1 - Mammakarzinommetastasen der Orbita. Radiologische Eigenschaften
AU - Akdag, F
AU - Hafezi, F
AU - Heule-Dieleman, H A G
AU - van den Bosch, W A
AU - Luyten, G P M
AU - Tanghe, H L J
AU - Paridaens, D
PY - 2010/8
Y1 - 2010/8
N2 - BACKGROUND: We reviewed the radiologic features of 15 patients with orbital metastases originating from breast cancer.METHODS: This was a retrospective consecutive case series. Fifteen consecutive patients with orbital metastases originating from breast carcinoma were identified between March 1997 and September 2008. A retrospective chart review was carried out, and the radiologic findings were reviewed.RESULTS: The metastases were preseptal in 53%, intraconal in 60%, and both intraconal and extraconal in 33%. Lacrimal gland enlargement was noted in 33%, episcleral space involvement in 33%, bone involvement in 13%, and globe dystopia in 53%. The extraocular muscles were involved in 87%; in 60%, two or more muscles were involved. The medial and lateral rectus muscles were affected in 53% and 47%, respectively, and the inferior and superior rectus muscles in 33%. In 47% one or more radiologic features had not been noted by the radiologist, and in 20% the findings were misinterpreted as an"orbital pseudotumor."CONCLUSION: Orbital metastases originating from breast cancer may present heterogeneously. Orbital imaging most commonly shows unilateral and multifocal involvement of multiple extraocular muscles and intraconal and preseptal areas by an irregular lesion.
AB - BACKGROUND: We reviewed the radiologic features of 15 patients with orbital metastases originating from breast cancer.METHODS: This was a retrospective consecutive case series. Fifteen consecutive patients with orbital metastases originating from breast carcinoma were identified between March 1997 and September 2008. A retrospective chart review was carried out, and the radiologic findings were reviewed.RESULTS: The metastases were preseptal in 53%, intraconal in 60%, and both intraconal and extraconal in 33%. Lacrimal gland enlargement was noted in 33%, episcleral space involvement in 33%, bone involvement in 13%, and globe dystopia in 53%. The extraocular muscles were involved in 87%; in 60%, two or more muscles were involved. The medial and lateral rectus muscles were affected in 53% and 47%, respectively, and the inferior and superior rectus muscles in 33%. In 47% one or more radiologic features had not been noted by the radiologist, and in 20% the findings were misinterpreted as an"orbital pseudotumor."CONCLUSION: Orbital metastases originating from breast cancer may present heterogeneously. Orbital imaging most commonly shows unilateral and multifocal involvement of multiple extraocular muscles and intraconal and preseptal areas by an irregular lesion.
KW - Adenocarcinoma/diagnosis
KW - Adenocarcinoma, Scirrhous/diagnosis
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Biopsy
KW - Breast Neoplasms/diagnosis
KW - Diagnosis, Differential
KW - Eye Diseases/diagnosis
KW - Female
KW - Humans
KW - Lymphatic Metastasis
KW - Magnetic Resonance Imaging
KW - Middle Aged
KW - Neoplasm Staging
KW - Orbit/pathology
KW - Orbital Neoplasms/diagnosis
KW - Retrospective Studies
KW - Tomography, X-Ray Computed
KW - Vision Disorders/diagnosis
U2 - 10.1007/s00347-009-2122-y
DO - 10.1007/s00347-009-2122-y
M3 - Artikel
C2 - 20393728
SN - 0941-293X
VL - 107
SP - 728
EP - 732
JO - Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
JF - Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
IS - 8
ER -