Malignant pleural mesothelioma with lacrimal gland metastasis

Hanida Hanafi; Rob M Verdijk; Dion Paridaens

doi:10.1111/aos.13163

Malignant pleural mesothelioma with lacrimal gland metastasis

Hanida Hanafi, Rob M Verdijk, Dion Paridaens

Orbita and oculoplastic surgery

Research output: Contribution to journal › Letter › peer-review

Abstract

PURPOSE: To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy.

METHODS: Interventional case report.

RESULTS: A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy.

CONCLUSIONS: Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.

Original language	English
Pages (from-to)	836-838
Number of pages	3
Journal	Acta Ophthalmologica
Volume	94
Issue number	8
DOIs	https://doi.org/10.1111/aos.13163
Publication status	Published - Dec 2016

Keywords

Biopsy
Carboplatin/therapeutic use
Chemoradiotherapy
Eye Neoplasms/diagnostic imaging
Female
Humans
Lacrimal Apparatus Diseases/diagnostic imaging
Lung Neoplasms/diagnostic imaging
Magnetic Resonance Imaging
Mesothelioma/diagnostic imaging
Middle Aged
Pleural Neoplasms/pathology

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10.1111/aos.13163

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title = "Malignant pleural mesothelioma with lacrimal gland metastasis",

abstract = "PURPOSE: To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy.METHODS: Interventional case report.RESULTS: A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy.CONCLUSIONS: Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.",

keywords = "Biopsy, Carboplatin/therapeutic use, Chemoradiotherapy, Eye Neoplasms/diagnostic imaging, Female, Humans, Lacrimal Apparatus Diseases/diagnostic imaging, Lung Neoplasms/diagnostic imaging, Magnetic Resonance Imaging, Mesothelioma/diagnostic imaging, Middle Aged, Pleural Neoplasms/pathology",

author = "Hanida Hanafi and Verdijk, \{Rob M\} and Dion Paridaens",

note = "{\textcopyright} 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley \& Sons Ltd.",

year = "2016",

month = dec,

doi = "10.1111/aos.13163",

language = "English",

volume = "94",

pages = "836--838",

number = "8",

}

TY - JOUR

T1 - Malignant pleural mesothelioma with lacrimal gland metastasis

AU - Hanafi, Hanida

AU - Verdijk, Rob M

AU - Paridaens, Dion

PY - 2016/12

Y1 - 2016/12

N2 - PURPOSE: To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy.METHODS: Interventional case report.RESULTS: A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy.CONCLUSIONS: Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.

AB - PURPOSE: To describe a rare clinical case of biopsy-proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy.METHODS: Interventional case report.RESULTS: A 55-year-old woman with an untreated malignant biopsy-proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy.CONCLUSIONS: Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.

KW - Biopsy

KW - Carboplatin/therapeutic use

KW - Chemoradiotherapy

KW - Eye Neoplasms/diagnostic imaging

KW - Female

KW - Humans

KW - Lacrimal Apparatus Diseases/diagnostic imaging

KW - Lung Neoplasms/diagnostic imaging

KW - Magnetic Resonance Imaging

KW - Mesothelioma/diagnostic imaging

KW - Middle Aged

KW - Pleural Neoplasms/pathology

U2 - 10.1111/aos.13163

DO - 10.1111/aos.13163

M3 - Letter

C2 - 27422678

SN - 1755-375X

VL - 94

SP - 836

EP - 838

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

IS - 8

ER -

Malignant pleural mesothelioma with lacrimal gland metastasis

Abstract

Keywords

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