TY - GEN
T1 - Locally-adaptive loosely-coupled level sets for retinal layer and fluid segmentation in subjects with central serous retinopathy
AU - Novosel, Jelena
AU - Wang, Ziyuan
AU - de Jong, Jan Hendrik
AU - van Velthoven, M E J
AU - Vermeer, Koenraad Arndt
AU - van Vliet, Lucas J
PY - 2016
Y1 - 2016
N2 - We present a locally-adaptive approach to segment the fluid and the interfaces between retinal layers in eyes affected by central serous retinopathy based on loosely-coupled level sets. The approach exploits the local attenuation coefficient differences of layers around an interface and introduces auxiliary interfaces to delineate the fluid. Thus, it can handle abrupt attenuation coefficient variations and topology-disrupting anomalies. The method was applied to in-vivo images of retinas acquired by optical coherence tomography. A quantitative comparison with manual annotations shows the method's high accuracy: we obtained a mean absolute deviation for the interfaces of 3.7-8.9 ßm (1-2 pixels) and a Dice coefficient for the fluid segmentation of 0.96.
AB - We present a locally-adaptive approach to segment the fluid and the interfaces between retinal layers in eyes affected by central serous retinopathy based on loosely-coupled level sets. The approach exploits the local attenuation coefficient differences of layers around an interface and introduces auxiliary interfaces to delineate the fluid. Thus, it can handle abrupt attenuation coefficient variations and topology-disrupting anomalies. The method was applied to in-vivo images of retinas acquired by optical coherence tomography. A quantitative comparison with manual annotations shows the method's high accuracy: we obtained a mean absolute deviation for the interfaces of 3.7-8.9 ßm (1-2 pixels) and a Dice coefficient for the fluid segmentation of 0.96.
U2 - 10.1109/ISBI.2016.7493363
DO - 10.1109/ISBI.2016.7493363
M3 - Conference contribution
SP - 702
EP - 705
BT - IEEE 13th International Symposium on Biomedical Imaging (ISBI)
ER -