HLA typing in birdshot chorioretinopathy

H A Priem; A Kijlstra; L Noens; G S Baarsma; J J De Laey; J A Oosterhuis

doi:10.1016/0002-9394(88)90183-3

HLA typing in birdshot chorioretinopathy

H A Priem, A Kijlstra, L Noens, G S Baarsma, J J De Laey, J A Oosterhuis

Medical retina and Uveitis

Research output: Contribution to journal › Article › Research › peer-review

Abstract

We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).

Original language	English
Pages (from-to)	182-185
Number of pages	4
Journal	American Journal of Ophthalmology
Volume	105
Issue number	2
DOIs	https://doi.org/10.1016/0002-9394(88)90183-3
Publication status	Published - 15 Feb 1988

Keywords

Choroid/immunology
HLA Antigens/analysis
HLA-A Antigens
HLA-B Antigens
HLA-B44 Antigen
Histocompatibility Testing
Humans
Retinal Diseases/diagnosis
Risk Factors
Uveal Diseases/diagnosis

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10.1016/0002-9394(88)90183-3

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title = "HLA typing in birdshot chorioretinopathy",

abstract = "We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).",

keywords = "Choroid/immunology, HLA Antigens/analysis, HLA-A Antigens, HLA-B Antigens, HLA-B44 Antigen, Histocompatibility Testing, Humans, Retinal Diseases/diagnosis, Risk Factors, Uveal Diseases/diagnosis",

author = "Priem, {H A} and A Kijlstra and L Noens and Baarsma, {G S} and {De Laey}, {J J} and Oosterhuis, {J A}",

year = "1988",

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doi = "10.1016/0002-9394(88)90183-3",

language = "English",

volume = "105",

pages = "182--185",

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T1 - HLA typing in birdshot chorioretinopathy

AU - Priem, H A

AU - Kijlstra, A

AU - Noens, L

AU - Baarsma, G S

AU - De Laey, J J

AU - Oosterhuis, J A

PY - 1988/2/15

Y1 - 1988/2/15

N2 - We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).

AB - We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).

KW - Choroid/immunology

KW - HLA Antigens/analysis

KW - HLA-A Antigens

KW - HLA-B Antigens

KW - HLA-B44 Antigen

KW - Histocompatibility Testing

KW - Humans

KW - Retinal Diseases/diagnosis

KW - Risk Factors

KW - Uveal Diseases/diagnosis

U2 - 10.1016/0002-9394(88)90183-3

DO - 10.1016/0002-9394(88)90183-3

M3 - Article

C2 - 3341436

SN - 0002-9394

VL - 105

SP - 182

EP - 185

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 2

ER -

HLA typing in birdshot chorioretinopathy

Abstract

Keywords

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