Histopathology of a vasoproliferative tumor of the ocular fundus

M H Smeets; C M Mooy; G S Baarsma; D E Mertens; J C Van Meurs

doi:10.1097/00006982-199805000-00016

Histopathology of a vasoproliferative tumor of the ocular fundus

M H Smeets, C M Mooy, G S Baarsma, D E Mertens, J C Van Meurs

Research output: Contribution to journal › Article › Professional › peer-review

Abstract

In young patients, the most frequently occurring retinal capillary hemangiomas are those that are part of the hereditary von Hippel's disease or syndrome, histologically best classified as hemangioblastomas. In older individuals, lesions of similar ophthalmoscopic appearance occur but they differ in other clinical features. On the basis of clinical characteristics and a presumed histogenesis and histopathology, Shields et al. proposed changing the name of the latter lesions from "presumed acquired hemangiomas" to the more descriptive "vasoproliferative tumors".
We describe a patient with such a vascular lesion of the peripheral retina, in whom we obtained a clinico-pathologic correlation.

Original language	English
Pages (from-to)	470-2
Number of pages	3
Journal	Retina
Volume	18
Issue number	5
DOIs	https://doi.org/10.1097/00006982-199805000-00016
Publication status	Published - 1998

Keywords

Adult
Antigens, CD34/metabolism
Biopsy
Collagen/metabolism
Endothelium, Vascular/metabolism
Factor VIII/metabolism
Fluorescein Angiography
Follow-Up Studies
Fundus Oculi
Hemangioma, Capillary/metabolism
Humans
Immunohistochemistry
Laminin/metabolism
Laser Coagulation
Male
Retinal Neoplasms/metabolism
Vitrectomy

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title = "Histopathology of a vasoproliferative tumor of the ocular fundus",

abstract = "In young patients, the most frequently occurring retinal capillary hemangiomas are those that are part of the hereditary von Hippel's disease or syndrome, histologically best classified as hemangioblastomas. In older individuals, lesions of similar ophthalmoscopic appearance occur but they differ in other clinical features. On the basis of clinical characteristics and a presumed histogenesis and histopathology, Shields et al. proposed changing the name of the latter lesions from {"}presumed acquired hemangiomas{"} to the more descriptive {"}vasoproliferative tumors{"}.We describe a patient with such a vascular lesion of the peripheral retina, in whom we obtained a clinico-pathologic correlation.",

keywords = "Adult, Antigens, CD34/metabolism, Biopsy, Collagen/metabolism, Endothelium, Vascular/metabolism, Factor VIII/metabolism, Fluorescein Angiography, Follow-Up Studies, Fundus Oculi, Hemangioma, Capillary/metabolism, Humans, Immunohistochemistry, Laminin/metabolism, Laser Coagulation, Male, Retinal Neoplasms/metabolism, Vitrectomy",

author = "Smeets, {M H} and Mooy, {C M} and Baarsma, {G S} and Mertens, {D E} and {Van Meurs}, {J C}",

year = "1998",

doi = "10.1097/00006982-199805000-00016",

language = "English",

volume = "18",

pages = "470--2",

journal = "Retina",

issn = "0275-004X",

number = "5",

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TY - JOUR

T1 - Histopathology of a vasoproliferative tumor of the ocular fundus

AU - Smeets, M H

AU - Mooy, C M

AU - Baarsma, G S

AU - Mertens, D E

AU - Van Meurs, J C

PY - 1998

Y1 - 1998

N2 - In young patients, the most frequently occurring retinal capillary hemangiomas are those that are part of the hereditary von Hippel's disease or syndrome, histologically best classified as hemangioblastomas. In older individuals, lesions of similar ophthalmoscopic appearance occur but they differ in other clinical features. On the basis of clinical characteristics and a presumed histogenesis and histopathology, Shields et al. proposed changing the name of the latter lesions from "presumed acquired hemangiomas" to the more descriptive "vasoproliferative tumors".We describe a patient with such a vascular lesion of the peripheral retina, in whom we obtained a clinico-pathologic correlation.

AB - In young patients, the most frequently occurring retinal capillary hemangiomas are those that are part of the hereditary von Hippel's disease or syndrome, histologically best classified as hemangioblastomas. In older individuals, lesions of similar ophthalmoscopic appearance occur but they differ in other clinical features. On the basis of clinical characteristics and a presumed histogenesis and histopathology, Shields et al. proposed changing the name of the latter lesions from "presumed acquired hemangiomas" to the more descriptive "vasoproliferative tumors".We describe a patient with such a vascular lesion of the peripheral retina, in whom we obtained a clinico-pathologic correlation.

KW - Adult

KW - Antigens, CD34/metabolism

KW - Biopsy

KW - Collagen/metabolism

KW - Endothelium, Vascular/metabolism

KW - Factor VIII/metabolism

KW - Fluorescein Angiography

KW - Follow-Up Studies

KW - Fundus Oculi

KW - Hemangioma, Capillary/metabolism

KW - Humans

KW - Immunohistochemistry

KW - Laminin/metabolism

KW - Laser Coagulation

KW - Male

KW - Retinal Neoplasms/metabolism

KW - Vitrectomy

U2 - 10.1097/00006982-199805000-00016

DO - 10.1097/00006982-199805000-00016

M3 - Article

C2 - 9801046

SN - 0275-004X

VL - 18

SP - 470

EP - 472

JO - Retina

JF - Retina

IS - 5

ER -

Histopathology of a vasoproliferative tumor of the ocular fundus

Abstract

Keywords

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