High incidence of corneal epithelium antibodies in Fuch's heterochromic cyclitis

Ellen La Hey; G S Baarsma; A Rothova; L Broersma; R van der Gaag; A Kijlstra

doi:10.1136/bjo.72.12.921

High incidence of corneal epithelium antibodies in Fuch's heterochromic cyclitis

Ellen La Hey, G S Baarsma, A Rothova, L Broersma, R van der Gaag, A Kijlstra

Medical retina and Uveitis

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Sera obtained from 26 patients with Fuchs' heterochromic cyclitis were examined for the presence of autoantibodies directed against the anterior segment of the eye by means of immunofluorescence techniques. Antibodies against human iris tissue could not be detected, whereas autoantibodies against corneal epithelium were found in almost 90% of cases. This is the first report describing the presence of autoantibodies in patients with Fuchs' heterochromic cyclitis and it provides a further clue that immunological mechanisms might play an important role in the aetiology of Fuchs' heterochromic cyclitis.

Original language	English
Pages (from-to)	921-5
Number of pages	5
Journal	British Journal of Ophthalmology
Volume	72
Issue number	12
DOIs	https://doi.org/10.1136/bjo.72.12.921
Publication status	Published - Dec 1988

Keywords

Adult
Autoantibodies/analysis
Ciliary Body/immunology
Cornea/immunology
Epithelium/immunology
Female
Fluorescent Antibody Technique
Humans
Iris/immunology
Male
Uveitis/etiology

Access to Document

10.1136/bjo.72.12.921

Cite this

@article{709c0c9cd36144ae88e81dd3ab0da2fc,

title = "High incidence of corneal epithelium antibodies in Fuch's heterochromic cyclitis",

abstract = "Sera obtained from 26 patients with Fuchs' heterochromic cyclitis were examined for the presence of autoantibodies directed against the anterior segment of the eye by means of immunofluorescence techniques. Antibodies against human iris tissue could not be detected, whereas autoantibodies against corneal epithelium were found in almost 90% of cases. This is the first report describing the presence of autoantibodies in patients with Fuchs' heterochromic cyclitis and it provides a further clue that immunological mechanisms might play an important role in the aetiology of Fuchs' heterochromic cyclitis.",

keywords = "Adult, Autoantibodies/analysis, Ciliary Body/immunology, Cornea/immunology, Epithelium/immunology, Female, Fluorescent Antibody Technique, Humans, Iris/immunology, Male, Uveitis/etiology",

author = "{La Hey}, Ellen and Baarsma, {G S} and A Rothova and L Broersma and {van der Gaag}, R and A Kijlstra",

year = "1988",

month = dec,

doi = "10.1136/bjo.72.12.921",

language = "English",

volume = "72",

pages = "921--5",

number = "12",

}

TY - JOUR

T1 - High incidence of corneal epithelium antibodies in Fuch's heterochromic cyclitis

AU - La Hey, Ellen

AU - Baarsma, G S

AU - Rothova, A

AU - Broersma, L

AU - van der Gaag, R

AU - Kijlstra, A

PY - 1988/12

Y1 - 1988/12

N2 - Sera obtained from 26 patients with Fuchs' heterochromic cyclitis were examined for the presence of autoantibodies directed against the anterior segment of the eye by means of immunofluorescence techniques. Antibodies against human iris tissue could not be detected, whereas autoantibodies against corneal epithelium were found in almost 90% of cases. This is the first report describing the presence of autoantibodies in patients with Fuchs' heterochromic cyclitis and it provides a further clue that immunological mechanisms might play an important role in the aetiology of Fuchs' heterochromic cyclitis.

AB - Sera obtained from 26 patients with Fuchs' heterochromic cyclitis were examined for the presence of autoantibodies directed against the anterior segment of the eye by means of immunofluorescence techniques. Antibodies against human iris tissue could not be detected, whereas autoantibodies against corneal epithelium were found in almost 90% of cases. This is the first report describing the presence of autoantibodies in patients with Fuchs' heterochromic cyclitis and it provides a further clue that immunological mechanisms might play an important role in the aetiology of Fuchs' heterochromic cyclitis.

KW - Adult

KW - Autoantibodies/analysis

KW - Ciliary Body/immunology

KW - Cornea/immunology

KW - Epithelium/immunology

KW - Female

KW - Fluorescent Antibody Technique

KW - Humans

KW - Iris/immunology

KW - Male

KW - Uveitis/etiology

U2 - 10.1136/bjo.72.12.921

DO - 10.1136/bjo.72.12.921

M3 - Article

C2 - 3067747

SN - 0007-1161

VL - 72

SP - 921

EP - 925

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

IS - 12

ER -

High incidence of corneal epithelium antibodies in Fuch's heterochromic cyclitis

Abstract

Keywords

Access to Document

Fingerprint

Cite this