PURPOSE: To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA).
METHODS: Interventional case report.
RESULTS: A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid.
CONCLUSIONS: Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.
|Number of pages||5|
|Journal||Orbit (Amsterdam, Netherlands)|
|Publication status||Published - Feb 2018|
- Antibodies, Monoclonal/adverse effects
- Arthritis, Rheumatoid/drug therapy
- Carcinoma, Merkel Cell/chemically induced
- Chronic Disease
- Combined Modality Therapy
- Dose Fractionation, Radiation
- Eyelid Neoplasms/chemically induced
- Immunosuppressive Agents/adverse effects
- Ophthalmologic Surgical Procedures
- Radiotherapy Dosage
- Reconstructive Surgical Procedures
- Tumor Necrosis Factor-alpha/antagonists & inhibitors