Endothelial cell density after posterior lamellar keratoplasty (Melles techniques): 3 years follow-up

Bart Van Dooren; Paul G H Mulder; Carla P Nieuwendaal; W H Beekhuis; Gerrit R J Melles

doi:10.1016/j.ajo.2004.02.016

Endothelial cell density after posterior lamellar keratoplasty (Melles techniques): 3 years follow-up

Bart Van Dooren, Paul G H Mulder, Carla P Nieuwendaal, W H Beekhuis, Gerrit R J Melles

Research output: Contribution to journal › Article › Research › peer-review

Abstract

PURPOSE: To report the midterm endothelial cell density measurements after posterior lamellar keratoplasty (Melles techniques).

DESIGN: Cohort study.

METHODS: Fifteen consecutive eyes of 15 patients in whom a posterior lamellar keratoplasty procedure was performed for pseudophakic bullous keratopathy or Fuchs' endothelial dystrophy were evaluated. In 11 corneas the donor tissue was inserted through a 9.0-mm sclerocorneal pocket incision (technique A); in four cases the donor was folded and inserted through a 5.0-mm incision (technique B). Specular microscopy was performed at 6, 12, 24, and 36 months after surgery, to measure the endothelial cell density.

RESULTS: Mean postoperative endothelial cell density averaged 2,126 cells/mm(2) (+/-548) at 6 months, 1,859 cells/mm(2) (+/-477) at 12 months, 1,385 cells/mm(2) (+/-451) at 24 months, and 1,047 cells/mm(2) (+/-425) at 36 months.

CONCLUSION: In posterior lamellar keratoplasty, the donor corneal endothelium showed a decrease in cell density similar to that after conventional full-thickness penetrating keratoplasty.

Original language	English
Pages (from-to)	211-7
Number of pages	7
Journal	American Journal of Ophthalmology
Volume	138
Issue number	2
DOIs	https://doi.org/10.1016/j.ajo.2004.02.016
Publication status	Published - Aug 2004

Keywords

Aged
Cell Count
Cohort Studies
Corneal Diseases/surgery
Corneal Transplantation
Endothelium, Corneal/pathology
Female
Follow-Up Studies
Humans
Male
Postoperative Complications

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10.1016/j.ajo.2004.02.016

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@article{87de5dd7a5de406584c8e6488e849a52,

title = "Endothelial cell density after posterior lamellar keratoplasty (Melles techniques): 3 years follow-up",

abstract = "PURPOSE: To report the midterm endothelial cell density measurements after posterior lamellar keratoplasty (Melles techniques).DESIGN: Cohort study.METHODS: Fifteen consecutive eyes of 15 patients in whom a posterior lamellar keratoplasty procedure was performed for pseudophakic bullous keratopathy or Fuchs' endothelial dystrophy were evaluated. In 11 corneas the donor tissue was inserted through a 9.0-mm sclerocorneal pocket incision (technique A); in four cases the donor was folded and inserted through a 5.0-mm incision (technique B). Specular microscopy was performed at 6, 12, 24, and 36 months after surgery, to measure the endothelial cell density.RESULTS: Mean postoperative endothelial cell density averaged 2,126 cells/mm(2) (+/-548) at 6 months, 1,859 cells/mm(2) (+/-477) at 12 months, 1,385 cells/mm(2) (+/-451) at 24 months, and 1,047 cells/mm(2) (+/-425) at 36 months.CONCLUSION: In posterior lamellar keratoplasty, the donor corneal endothelium showed a decrease in cell density similar to that after conventional full-thickness penetrating keratoplasty.",

keywords = "Aged, Cell Count, Cohort Studies, Corneal Diseases/surgery, Corneal Transplantation, Endothelium, Corneal/pathology, Female, Follow-Up Studies, Humans, Male, Postoperative Complications",

author = "{Van Dooren}, Bart and Mulder, {Paul G H} and Nieuwendaal, {Carla P} and Beekhuis, {W H} and Melles, {Gerrit R J}",

year = "2004",

month = aug,

doi = "10.1016/j.ajo.2004.02.016",

language = "English",

volume = "138",

pages = "211--7",

number = "2",

}

TY - JOUR

T1 - Endothelial cell density after posterior lamellar keratoplasty (Melles techniques)

T2 - 3 years follow-up

AU - Van Dooren, Bart

AU - Mulder, Paul G H

AU - Nieuwendaal, Carla P

AU - Beekhuis, W H

AU - Melles, Gerrit R J

PY - 2004/8

Y1 - 2004/8

N2 - PURPOSE: To report the midterm endothelial cell density measurements after posterior lamellar keratoplasty (Melles techniques).DESIGN: Cohort study.METHODS: Fifteen consecutive eyes of 15 patients in whom a posterior lamellar keratoplasty procedure was performed for pseudophakic bullous keratopathy or Fuchs' endothelial dystrophy were evaluated. In 11 corneas the donor tissue was inserted through a 9.0-mm sclerocorneal pocket incision (technique A); in four cases the donor was folded and inserted through a 5.0-mm incision (technique B). Specular microscopy was performed at 6, 12, 24, and 36 months after surgery, to measure the endothelial cell density.RESULTS: Mean postoperative endothelial cell density averaged 2,126 cells/mm(2) (+/-548) at 6 months, 1,859 cells/mm(2) (+/-477) at 12 months, 1,385 cells/mm(2) (+/-451) at 24 months, and 1,047 cells/mm(2) (+/-425) at 36 months.CONCLUSION: In posterior lamellar keratoplasty, the donor corneal endothelium showed a decrease in cell density similar to that after conventional full-thickness penetrating keratoplasty.

AB - PURPOSE: To report the midterm endothelial cell density measurements after posterior lamellar keratoplasty (Melles techniques).DESIGN: Cohort study.METHODS: Fifteen consecutive eyes of 15 patients in whom a posterior lamellar keratoplasty procedure was performed for pseudophakic bullous keratopathy or Fuchs' endothelial dystrophy were evaluated. In 11 corneas the donor tissue was inserted through a 9.0-mm sclerocorneal pocket incision (technique A); in four cases the donor was folded and inserted through a 5.0-mm incision (technique B). Specular microscopy was performed at 6, 12, 24, and 36 months after surgery, to measure the endothelial cell density.RESULTS: Mean postoperative endothelial cell density averaged 2,126 cells/mm(2) (+/-548) at 6 months, 1,859 cells/mm(2) (+/-477) at 12 months, 1,385 cells/mm(2) (+/-451) at 24 months, and 1,047 cells/mm(2) (+/-425) at 36 months.CONCLUSION: In posterior lamellar keratoplasty, the donor corneal endothelium showed a decrease in cell density similar to that after conventional full-thickness penetrating keratoplasty.

KW - Aged

KW - Cell Count

KW - Cohort Studies

KW - Corneal Diseases/surgery

KW - Corneal Transplantation

KW - Endothelium, Corneal/pathology

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Postoperative Complications

U2 - 10.1016/j.ajo.2004.02.016

DO - 10.1016/j.ajo.2004.02.016

M3 - Article

C2 - 15289129

SN - 0002-9394

VL - 138

SP - 211

EP - 217

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 2

ER -

Endothelial cell density after posterior lamellar keratoplasty (Melles techniques): 3 years follow-up

Abstract

Keywords

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