Cytology of human intraocular lenses. A scanning electron microscopic study

J P Kappelhof, G F Vrensen, P T de Jong, J H Pameyer, B L Willekens

    Research output: Contribution to journalArticleProfessionalpeer-review


    Scanning electron microscopy of 9 intraocular lenses, removed from patients mainly because of corneal problems, revealed the presence of different types of adhering elements. Independent of clinically significant symptoms of infection, macrophages and/or epitheloid cells and/or granulocytes were observed. On their anterior surface, 3 lenses showed flat cells or cellular remains which are supposed to represent corneal epithelial cells. Membrane fragments were found on 3 other lenses. Most of the polymethylmethacrylate optics of the lenses showed some deformation and/or cracking and to evaluate them some additional studies with new intraocular lenses were performed. High pressure during the preparation procedure for scanning electron microscopy was found to be the cause.

    Original languageEnglish
    Pages (from-to)75-80
    Number of pages6
    JournalOphthalmic Research
    Issue number2
    Publication statusPublished - 1986


    • Cell Adhesion
    • Cornea/cytology
    • Corneal Diseases/surgery
    • Endothelium/cytology
    • Fibroblasts/cytology
    • Humans
    • Lenses, Intraocular
    • Microscopy, Electron, Scanning
    • Prosthesis Failure
    • Time Factors


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