Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable

Claus Cursiefen; Joseph Colin; Reza Dana; Manuel Diaz-Llopis; Lana A Faraj; Salvador Garcia-Delpech; Gerd Geerling; Francis W Price; Lies Remeijer; Barry T Rouse; Berthold Seitz; Patricia Udaondo; Daniel Meller; Harminder Dua

doi:10.1136/bjo.2011.204701

Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable

Claus Cursiefen, Joseph Colin, Reza Dana, Manuel Diaz-Llopis, Lana A Faraj, Salvador Garcia-Delpech, Gerd Geerling, Francis W Price, Lies Remeijer, Barry T Rouse, Berthold Seitz, Patricia Udaondo, Daniel Meller, Harminder Dua

Cornea

Research output: Contribution to journal › Review article › peer-review

Abstract

The cornea is the clear window at the front of the eye and is the eye's main refractive medium. Its transparency is essential for vision. Corneal neovascularisation is a common clinical problem with serious consequences for vision; it can compromise corneal transparency and plays a major role in corneal graft rejection by breaching corneal immune privilege. In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs.

Original language	English
Pages (from-to)	3-9
Number of pages	7
Journal	British Journal of Ophthalmology
Volume	96
Issue number	1
DOIs	https://doi.org/10.1136/bjo.2011.204701
Publication status	Published - Jan 2012

Keywords

Angiogenesis Inhibitors/therapeutic use
Corneal Diseases/drug therapy
Corneal Neovascularization/drug therapy
Humans
Ophthalmology/standards
Practice Guidelines as Topic

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10.1136/bjo.2011.204701

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Cursiefen, C., Colin, J., Dana, R., Diaz-Llopis, M., Faraj, L. A., Garcia-Delpech, S., Geerling, G., Price, F. W., Remeijer, L., Rouse, B. T., Seitz, B., Udaondo, P., Meller, D., & Dua, H. (2012). Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable. British Journal of Ophthalmology, 96(1), 3-9. https://doi.org/10.1136/bjo.2011.204701

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title = "Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable",

abstract = "The cornea is the clear window at the front of the eye and is the eye's main refractive medium. Its transparency is essential for vision. Corneal neovascularisation is a common clinical problem with serious consequences for vision; it can compromise corneal transparency and plays a major role in corneal graft rejection by breaching corneal immune privilege. In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs.",

keywords = "Angiogenesis Inhibitors/therapeutic use, Corneal Diseases/drug therapy, Corneal Neovascularization/drug therapy, Humans, Ophthalmology/standards, Practice Guidelines as Topic",

author = "Claus Cursiefen and Joseph Colin and Reza Dana and Manuel Diaz-Llopis and Faraj, {Lana A} and Salvador Garcia-Delpech and Gerd Geerling and Price, {Francis W} and Lies Remeijer and Rouse, {Barry T} and Berthold Seitz and Patricia Udaondo and Daniel Meller and Harminder Dua",

year = "2012",

month = jan,

doi = "10.1136/bjo.2011.204701",

language = "English",

volume = "96",

pages = "3--9",

number = "1",

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Cursiefen, C, Colin, J, Dana, R, Diaz-Llopis, M, Faraj, LA, Garcia-Delpech, S, Geerling, G, Price, FW, Remeijer, L, Rouse, BT, Seitz, B, Udaondo, P, Meller, D & Dua, H 2012, 'Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable', British Journal of Ophthalmology, vol. 96, no. 1, pp. 3-9. https://doi.org/10.1136/bjo.2011.204701

TY - JOUR

T1 - Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation

T2 - outcome of an expert roundtable

AU - Cursiefen, Claus

AU - Colin, Joseph

AU - Dana, Reza

AU - Diaz-Llopis, Manuel

AU - Faraj, Lana A

AU - Garcia-Delpech, Salvador

AU - Geerling, Gerd

AU - Price, Francis W

AU - Remeijer, Lies

AU - Rouse, Barry T

AU - Seitz, Berthold

AU - Udaondo, Patricia

AU - Meller, Daniel

AU - Dua, Harminder

PY - 2012/1

Y1 - 2012/1

N2 - The cornea is the clear window at the front of the eye and is the eye's main refractive medium. Its transparency is essential for vision. Corneal neovascularisation is a common clinical problem with serious consequences for vision; it can compromise corneal transparency and plays a major role in corneal graft rejection by breaching corneal immune privilege. In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs.

AB - The cornea is the clear window at the front of the eye and is the eye's main refractive medium. Its transparency is essential for vision. Corneal neovascularisation is a common clinical problem with serious consequences for vision; it can compromise corneal transparency and plays a major role in corneal graft rejection by breaching corneal immune privilege. In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs.

KW - Angiogenesis Inhibitors/therapeutic use

KW - Corneal Diseases/drug therapy

KW - Corneal Neovascularization/drug therapy

KW - Humans

KW - Ophthalmology/standards

KW - Practice Guidelines as Topic

U2 - 10.1136/bjo.2011.204701

DO - 10.1136/bjo.2011.204701

M3 - Review article

C2 - 21712359

SN - 0007-1161

VL - 96

SP - 3

EP - 9

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

IS - 1

ER -

Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable

Abstract

Keywords

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