Alexandre Matet, Suzanne Yzer, Emily Y Chew, Alejandra Daruich, Francine Behar-Cohen, Richard F Spaide

Research output: Contribution to journalArticleResearchpeer-review


PURPOSE: To describe cases presenting with features of idiopathic macular telangiectasia (MacTel) Type 2 and central serous chorioretinopathy (CSC).

METHODS: Databases from four tertiary retina centers were searched for cases copresenting CSC and MacTel Type 2.

RESULTS: Five cases were identified (4 men, 1 woman; mean age: 67.2 years). Four patients were referred for chronic or nonresolving CSC, and the diagnosis of MacTel Type 2 was made based on multimodal imaging findings. One patient had advanced MacTel Type 2, and developed acute CSC. Regarding the MacTel Type 2 findings, all subjects presented perifoveal telangiectasia on fluorescein angiography, and four subjects showed intraretinal cavitations typical of MacTel Type 2 on optical coherence tomography, in one or both eyes. Regarding the CSC findings, fluorescein angiography identified focal or extended retinal pigment epithelium alteration in all eyes, and an active leakage in two eyes. Indocyanine green angiography showed choroidal vascular hyperpermeability in four subjects. On optical coherence tomography, pigment epithelial detachments were detected in five eyes (four subjects), and foveal detachments were present in five eyes (three subjects), which spontaneously resolved (two eyes), responded to photodynamic therapy (two eyes), or persisted (one eye). Mean choroidal thickness was 402 ± 99 μm.

CONCLUSION: The codiagnosis of CSC and MacTel Type 2 should be considered in atypical presentations associating features from both disorders.

Original languageEnglish
Pages (from-to)S67-S78
Volume38 Suppl 1
Publication statusPublished - Jan 2018


  • Aged
  • Central Serous Chorioretinopathy/complications
  • Choroid/pathology
  • Female
  • Fluorescein Angiography/methods
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Macula Lutea/pathology
  • Male
  • Middle Aged
  • Retina
  • Retrospective Studies
  • Telangiectasia, Hereditary Hemorrhagic/complications
  • Tomography, Optical Coherence/methods
  • Visual Acuity


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