Birdshot chorioretinopathy and Lyme borreliosis

M S Suttorp-Schulten, L Luyendijk, A P van Dam, R J W de Keizer, G S Baarsma, P J M Bos, A Rothova

Research output: Contribution to journalArticleProfessionalpeer-review


Two patients in whom ocular Lyme disease was suspected and who had antibodies to Borrelia burgdorferi developed birdshot chorioretinopathy and carried the HLA-A29 antigen. In a series of 11 patients with birdshot chorioretinopathy who carried the HLA-A29 antigen, three patients had antibodies against B. burgdorferi as determined by either immunofluorescence assay, enzyme-linked immunosorbent assay, Western blot analysis, or a combination of these tests. Further studies will be necessary to evaluate whether this is a false-positive reaction or whether B. burgdorferi has a causative role in the pathogenesis of birdshot chorioretinopathy.

Original languageEnglish
Pages (from-to)149-53
Number of pages5
JournalAmerican Journal of Ophthalmology
Issue number2
Publication statusPublished - 15 Feb 1993


  • Blotting, Western
  • Borrelia burgdorferi Group/isolation & purification
  • Chorioretinitis/diagnostic imaging
  • Enzyme-Linked Immunosorbent Assay
  • False Positive Reactions
  • Fluorescein Angiography
  • Fluorescent Antibody Technique
  • HLA-A Antigens/analysis
  • Humans
  • Lyme Disease/complications
  • Radiography
  • Visual Acuity


Dive into the research topics of 'Birdshot chorioretinopathy and Lyme borreliosis'. Together they form a unique fingerprint.

Cite this