Autologous Translocation of the Retinal Pigment Epithelium and Choroid in the Treatment of Exudative Age-related Macular Degeneration

Kristel Maaijwee

    Research output: Types of ThesisDoctoral Thesis

    Abstract

    Age-related macular degeneration (AMD) is the most important cause of irreversible legal blindness in elderly persons in industrialized countries. AMD has two forms: atrophic (dry) and exudative (wet). In the wet form, abnormal blood vessels, arising from the choriocapillaris (choroidal neovascularization, CNV) underneath the macula, grow through ruptures in the Bruch’s membrane, into the sub-retinal pigment epithelium (RPE) space or into the subretinal space, or a combination of both. Blood and serum leakage from the CNV below the RPE and/or below and within the retina are harmful and fi nally causes irreversible damage to the photoreceptors of the overlying macula which results in a central scotoma.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    Supervisors/Advisors
    • van Meurs, Jan, Supervisor
    Publication statusPublished - 2008

    Fingerprint

    Dive into the research topics of 'Autologous Translocation of the Retinal Pigment Epithelium and Choroid in the Treatment of Exudative Age-related Macular Degeneration'. Together they form a unique fingerprint.

    Cite this